Product Features BioFreeze 3 oz. Roll-on is beneficial for acute pain; the spray is particularly beneficial for acute conditions involving severe muscle spasms of the lower back or acute spasms of the upper back or neck BioFreeze 3 oz. Roll-on is a unique, effective analgesic formulated to provide a variety of benefits for therapy, pain relief, exercise/training and overall comfort. It effectively helps relieve pain from Sore Muscles & Muscle Sprains, Back, Shoulder,Neck Pain, Arthritis, Painful Ankle, Knee, Hip & Elbow Joints, Muscular Strains. The result is a fast acting, deep penetrating, and long lasting pain reliever. BIOFREEZE products contain ILEX, an herbal extract from a South American holly shrub. ILEX is used around the world in various health & wellness formulations. BIOFREEZE topical analgesic does not use waxes, oils, aloe or petroleum. The result is a fast-acting, penetrating, long lasting pain reliever